Biochemistry & Medicine
  • Biochemistry  can  be  defined  as  the  science 
   concerned with the chemical basis of life. 
  • Biochemistry can be described as the science 
   concerned with the chemical constituents of 
   living  cells  and  with  the  reactions  and 
   processes they undergo. 
     A reciprocal relationship between
       biochemistry & medicine
  • Normal biochemical process are the basis of health.
  • The Aim of biochemistry is to describe & explain, 
   all chemical processes of living cells.
  • Most & perhaps all disease has a biochemical basis.
                             Water  
      • Water plays a central role in the chemistry of 
        all life
      • The chemical properties of water are related to 
        the functions of biomolecules, entire cells, and 
        organisms 
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                        The Water Molecule is Polar
       • Important  properties  of  water  arise  from  its 
         angled shape 
       •                     o
         Angle of 104.5  between two covalent bonds
       • Polar  O-H  bonds  due  to  uneven  distribution  of 
                                 -                   +
         charge (oxygen (d), hydrogen (d ))
       • Angled  arrangement  of  polar  bonds  creates  a 
         permanent dipole for a water molecule 
                                                                          5
     (a) Space-filling structure of water (b) Covalent 
                       bond angle of water
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